Effect of selected socio-demographic, clinical and biochemical factors on self-reported quality of life among post-menopausal women with osteoporosis.

INTRODUCTION The goal of health care with relation to women with osteoporosis is the prevention of fractures, maintenance of independence, and good quality of life. OBJECTIVE To discover how selected socio-demographic, clinical and biochemical factors affect positively or negatively the overall assessment of the quality of life, and to assess the quality of life in specific domains among women with osteoporosis. MATERIALS AND METHODS The study group covered 85 women with osteoporosis. Self-reported quality of life was evaluated using WHOQOL-100. In order to determine factors affecting the self-reported of quality of life the logistic regression analysis was applied. RESULTS The physical domain was associated with decreased height (OR=2.13; 95%CI 1.04-4.35), anxiety (OR=1.30; 95%CI 1.14-1.49) and depression (OR=1.32; 95%CI 1.09-1.59). The psychological domain was associated with previous fractures (OR=4.76; 95%CI 2.22-11.11), deformities of the back (OR=2.13; 95%CI 1.08-4.17) and anxiety (OR=1.16; 95%CI 1.02-1.16). The level of independence and of social domain were associated with performance of occupational activity, respectively (OR=0.93; 95%CI 0.88-0.97) (OR=0.96; 95%CI 0.88-0.98). The social domain was associated with decreased height (OR=2.38; 95%CI 1.12-5.26), deformities of the back (OR=1.28; 95%CI 1.02-4.35), BMI (OR=1.14; 95%CI 1.05-1.23), anxiety (OR=1.41; 95%CI 1.20-1.64) and depression (OR=1.23; 95%CI 1.03-1.49). CONCLUSION The factors determining poor quality of life were decreased height, deformity of the back, previous fractures, elevated FSH level, anxiety and depression. The factors determining a good self-reported quality of life were higher level of education and occupational activity.